Meyers, who has Usher syndrome and classes herself as a deaf-blind athlete, won three titles at Rio 2016.

The American withdrew from the Tokyo 2020 Paralympics last year after being denied her request for a personal care assistant because delegation sizes has been cut due to the COVID-19 pandemic.

Meyers announced her retirement via a letter to her six-year-old self on social media.

"Don’t worry, your disabilities won’t hold you back from achieving your dreams," Meyers wrote on Instagram, addressing how her disability did not stop her from achieving her dreams.

"Swimming will bring you happiness in ways you can’t even begin to imagine."

Meyers listed achievements from her career starting with finishing in first place at a mini-meet, and went on to mention becoming a National Collegiate Athletic Association finalist in Division III as well as the numerous medals won on the elite stage.

She was also twice named the ESPY Awards winner for best female athlete with a disability, in 2015 and 2017.

"As you turn the page to the next chapter of your life, be sure to cherish your memories of laughter, tears, hard work, happiness, adventures and lessons that the sport of swimming has given you," she added .

Meyers is still a world record-holder in 10 categories across freestyle, butterfly and the individual medley.